Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
Common Side Effects is an adult animated series that follows Marshall Cuso, a mycology expert, and his high school friend, Frances Applewhite. Marshall discovers the Blue Angel Mushroom, a rare fungus with extraordinary healing properties, capable of curing any illness. As they attempt to bring this medical breakthrough to the public, they uncover a conspiracy involving Reutical Pharmaceuticals and government agencies determined to suppress the mushroom's existence to protect their interests.
Throughout the series, Marshall and Frances navigate dangerous situations, including evading bounty hunters and law enforcement, while grappling with ethical dilemmas about the mushroom's potential impact on society. The narrative delves into themes of corporate greed, environmental pollution, and the complexities of friendship under pressure. The show's unique animation style and dark humor provide a satirical lens on the pharmaceutical industry and governmental corruption.